Esophageal Ulcer Induced by Alendronate / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy
;
: 25-28, 2004.
Article
in Korean
| WPRIM
| ID: wpr-40075
ABSTRACT
Alendronate sodium (Fosamax(R)) is an aminophosphonate used in treatment of postmenopausal osteoporosis by inhibition of osteoclastic activity. Esophageal ulcers related to alendronate use have been reported at the rate of 2~6%. However, there have been no reports of esophagitis or esophageal ulcer by alendronate in Korea. We present a case of esophageal ulcer caused by alendronate. The patient presented with retrosternal pain and severe odynophagia for a few days. Esophagogastroduodenoscopy revealed multiple deep ulcers at the esophagus. Her symptoms resolved completely after stopping alendronate. A follow-up esophagogastroduodenoscopy 6 weeks later revealed complete healing of the ulcers.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteoclasts
/
Ulcer
/
Osteoporosis, Postmenopausal
/
Follow-Up Studies
/
Endoscopy, Digestive System
/
Alendronate
/
Esophagitis
/
Esophagus
/
Korea
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Gastrointestinal Endoscopy
Year:
2004
Type:
Article
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