Association of Chlamydophila pneumoniae, Cytomegalovirus, Helicobacter pylori and HIV Infections with Myocardial Infarction / 대한임상미생물학회지
Korean Journal of Clinical Microbiology
;
: 41-46, 2005.
Article
in Korean
| WPRIM
| ID: wpr-40111
ABSTRACT
BACKGROUND:
There is some evidence linking the infections with common organisms such as Chlamydophila pneumoniae, cytomegalovirus (CMV), Helicobacter pylori and HIV to myocardial infarction (MI). We had performed a serologic study to assess whether C.pneumoniae, CMV, H. pylori and HIV infections are associated with MI.METHODS:
Serum samples were obtained from 54 cases of acute MI, 33 cases of old MI, and 60 normal controls. C-reactive protein (CRP) as an inflammation marker was measured and antibodies to C.pneumoniae, CMV, H.pylori and HIV were assayed by ELISA. Odds ratios (OR) were calculated against control group.RESULTS:
CRP was significantly higher in the acute MI and old MI group. ORs of C.pneumoniae infection increased considerably in the acute MI (IgM 1.57, IgG 4.80) and old MI group (IgM 2.42, IgG 5.18). ORs of CMV infection were 3.30 in the acute MI and 5.12 in old MI group. ORs of H. pylori infection showed below 1 in the acute MI and old MI. Anti-HIV antibody showed all negative result in three groups, so OR could not be calculated.CONCLUSION:
C.pneumoniae and CMV infections appear to be risk factors for MI.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Coronary Artery Disease
/
C-Reactive Protein
/
Immunoglobulin G
/
Enzyme-Linked Immunosorbent Assay
/
HIV Infections
/
Odds Ratio
/
Risk Factors
/
Helicobacter pylori
/
HIV
/
Helicobacter
Type of study:
Etiology study
/
Risk factors
Language:
Korean
Journal:
Korean Journal of Clinical Microbiology
Year:
2005
Type:
Article
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