A clinical and etiological analysis of candida urinary tract infections in intensive care unit / 中国医师进修杂志

ABSTRACT

Objective To investigate the clinical characteristics, risk factors and pathogenic disposition of candida urinary tract infections in intensive care unit(ICU)patients. Methods A retrospective review and analysis of clinical information and urine culture of 83 ICU patients with the candida urinary tract infections. Results All patients had severe underlying diseases one or more complication and/or concomitant diseases were existed at the same time. All of the patients previously used broad-spectrum antibiotics and received invasion in diagnosis and therapy indwelling urinary catheters, mechanical ventilation, incision of trachea, deep artery or vein operation with catheters indwelling, surgical operation and indwelling drainage tube (96.39%, 95.18%, 69.89%, 46.99%, 43.37%, 33.73%, respectively). In all the patients, 62.65% patients were elder. Hospitalization days of 54.22% patients staying in ICU were above 31 days. Mortality rate was in 39.76%( 33 cases ). C.tropicalis(55.91%) and C.albicans(35.48%) were the major pathogens. Seventy-four cases( 89.16%)were infected by one candida specie, and 9 cases( 10.84% )were infected by two or three candida species. The positive blood culture was found in 9 cases ( 10.84% ) also. Conclusions The ICU patients with severe underlying diseases and high risk factors may have candida urinary tract infections easily. C.tropicalis and C.albicans are the most common pathogens. Some candiduria is the evidence of candidemia.