Clinical values of serum CA19-9 in diseases of biliary system / 中华肝胆外科杂志

ABSTRACT

Objective To evaluate the clinical values of serum CA19-9 measurements in diseases Of biliary system.Methods Serum concentration of the CA19-9 antigen was determined in 621 patients with biliary diseases.Their serum bilirubin levels,operative managements,pathological factors and survivals were also analyzed.Results The highest effective percentage(93.9%)was observed at the CUt-off value of 37U/ml of serum CA19-9 level.Compared with benign disease group,it had a significant difference of the positive rate in malignant disease group of biliary system.A significant higher sensitivity rate and lower specificity rate were observed in patients with jaundice than those without jaundice.Conclusions The measurement of serum CA19-9 level has a important value for the diagnosis,operative management and prognosis of biliary system diseases.though a confident discrimination between benign and malignant jaundice could not be made on the basis of its elevation.