Effect of Astragalus on T Lymphocyte Immune Function in Immature Rats with Obstructive Jaundice / 国际中医中药杂志
International Journal of Traditional Chinese Medicine
;
(6): 87-89, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-402035
ABSTRACT
Objective To evaluate the effect of Astragalus on T lymphocyte immune function in peripheral blood and intestinal mucosa of immature rats with obstructive jaundice. Methods Three-week-old Wistar rats were randomly divided into four groups(n=12,in each)control group, sham operation group, obstructive jaundice(OJ)group,OJ+Astragalus (OJ+A)group.The percentage of CD4 and CD8 T lymphocytes, the ratio of CD4 to CD8 in peripheral blood and intestinal mucosa of immature rats was detected by flow cytometry. Result The percentage of CD4+ cell and the ratio of CD4 to CD8 in the OJ group were lower than those in the control group and the sham operation group,with significant difference(P<0.05).The percentage of CD4 cell and the ratio of CD4 to CD8 in the OJ+A group were higher than those in the OJ group(P<0.05).Conclusion Astragalus can increase T lymphocyte immune function in OJ immature rats.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Traditional Chinese Medicine
Year:
2008
Type:
Article
Similar
MEDLINE
...
LILACS
LIS