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Research on Realgar Inducing Apoptosis of Leukemia / 国际中医中药杂志
International Journal of Traditional Chinese Medicine ; (6): 92-93, 2008.
Article in Chinese | WPRIM | ID: wpr-402052
ABSTRACT
Objective To study the influence of realgar on apoptosis and Bcl-2 expression of leukemia.Methods Realgar treatment group and adriamycin(ADR)treatment group were established,and the indexes involved with OD value of cell strain,morphologic alteration of apoptosis,and positive expressive rate of Bcl-2 were observed in the two groups.Results Compared with ADR treatment group,OD value and Bcl-s positive expressive rate were significantly decreased(P<0.05)and apoptotic rate was significantly increased in realgar group(P<0.05).Conclusion Realgar has excellent effect to induce apoptosis of leukemia.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Traditional Chinese Medicine Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Traditional Chinese Medicine Year: 2008 Type: Article