The detection of postoperative hematogenous dissemination of colorectal cancer / 中华普通外科杂志
Chinese Journal of General Surgery
;
(12): 118-119, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-402181
ABSTRACT
Objective To study the significance of monitoring postoperative hematogenous micrometastasis of colorectal cancer. Methods The micrometastatic cancer cells in peripheral blood and bone marrow of the perioperative patients were investigated by CK20 mRNA RT-PCR. Results The positive rates(16.3%) of hematogenous dissemination without relapse or metastasis after operation were significantly lower than that(88.9%) in patients with postoperative relapse or metastasis. There were four types of hematogenous dissemination. (1) Postoperative temporary negatives.(2)Consistant positives. (3) CK-20 turned positive postoperatively. (4) Consistant negatives. All the 6 patients that died had positive CK-20 preoperatively. Conclusions The hematogenous dissemination of colorectal cancer plays an important role in postoperative relapse. The dynamic monitoring of CK-20 predicts hematogenous dissemination of colorectal cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Chinese Journal of General Surgery
Year:
2001
Type:
Article
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