A Case of Infantile Digital Fibromatosis
Annals of Dermatology
;
: 174-178, 1999.
Article
in English
| WPRIM
| ID: wpr-40254
ABSTRACT
We report a case of infantile digital fibromatosis in a 34 month-old boy, who presented with a painless subcutaneous tumor on the medial aspect of the left third toe. A histological examination showed scattered small, round eosinophilic inclusion bodies in the cytoplasm of the tumor cells, which was consistent with infantile digital fibromatosis. A'immunohistochemical study revealed that desmin, a-smooth muscle actin, and vimentin were clearly positive in the cytoplasm of the tumor cells, but the inclusions themselves showed negative staining, thus indicating a hollow-like staining pattern. Electron microscopy showed either well-defined or ill-demarcated dense bodies in the cytoplasm of the tumor cells. In some areas, small vesicles and intracellular organells were observed' in the inclusions. In the course of conservative treatment, a new lesion developed on the lateral aspect of the left third toe, seven months after the appearance of the initial lesion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vimentin
/
Microscopy, Electron
/
Toes
/
Inclusion Bodies
/
Actins
/
Negative Staining
/
Cytoplasm
/
Desmin
/
Eosinophils
/
Fibroma
Limits:
Humans
/
Male
Language:
English
Journal:
Annals of Dermatology
Year:
1999
Type:
Article
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