Logistic regression analysis of risk factors for lumbar disc herniation in adolescents in Jinzhou city / 中国组织工程研究

ABSTRACT

BACKGROUND:The pathogenesis and risk factors for lumbar disc herniation are significantly different between adults and teenagers Previous studies seldomly refer to risk factors for lumbar disc herniation in adolescents by using logistic regression analysis.OBJECTIVE:To investigate the risk factors for lumbar disc herniation in adolescents in Jinzhou by using logistic regression analysis.METHODS:A total of 94 patients with lumbar disc herniation,including 56 males and 38 females,aging 9-18 years,were considered as the experimental group.A total of 1 00 patients suffering from other diseases were considered as the control group.Logistic regression analysis was employed to analyze risk factors for lumbar disc herniation onset,suggesting that OR>1 was taken as the risk factor for lumbar disc herniation,whereas OR<1 as the protective factor for lumbar disc herniation RESULTS AND CONCLUSION:All the 1 94 patients were involved in the final analysis.The result of logistic regression analysis showed that compared with control groups,the patients with lumbar disc herniation were statistically associated with familial Dredisposition(OR=6.427,P=0 015),trauma(OR=17.196,P=0.011),congenitalmalformations(OR=31.429,P=0 002),and over-exercise(OR=12.644,P=0.027)Trauma,congenital malformations,familial predisposition,and over-exercise were the risk factors for lumbar disc herniation in children and adolescents in Jinzhou.So it is necessary to implement a comprehensive prevention program,such as lifestyle and dietary habit modification,and proper activity.