The chemokine receptors CXCR4 and CXCR7 in cancer / 中国癌症杂志
China Oncology
;
(12): 222-226, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-402885
ABSTRACT
CXCR4 has long been considered as the unique receptor of CXCL12,and CXCL12/CXCR4 axis plays a prominent role in tumorigenesis.However,a novel receptor for CXCL12,named CXCR7,has been recently identified and also plays an important role in tumorigenesis.This review summarized current studies regarding the functions of CXCR4 and CXCR7 in cancer and the recent therapeutic approaches that target these receptors or their ligands.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Oncology
Year:
2010
Type:
Article
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