Pegylated Interferon-Associated Severe Retinopathy in a Patient with Chronic Hepatitis
Korean Journal of Ophthalmology
;
: 147-150, 2012.
Article
in English
| WPRIM
| ID: wpr-40414
ABSTRACT
This paper reports a case of pegylated interferon-associated retinopathy in a patient with chronic hepatitis C. A 32-year-old female with chronic hepatitis C undergoing pegylated interferon and ribavirin combination therapy complained of visual blurring. Features of interferon-associated retinopathy, including ocular complications such as cotton wool spots, retinal hemorrhages, macular edema, and branch retinal vein occlusion, were found in the fundus of both of her eyes. Pegylated interferon combination therapy was stopped, and the retinopathy of the patient was treated with intravitreal bevacizumab injections and panretinal photocoagulations. This case shows that pharmacokinetically improved pegylated interferon has ocular complications for patients with chronic hepatitis C. Accordingly, patients undergoing pegylated interferon treatment for hepatitis C need regular eye examinations for protection of their vision.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Antiviral Agents
/
Polyethylene Glycols
/
Retinitis
/
Severity of Illness Index
/
Recombinant Proteins
/
Interferon-alpha
/
Hepatitis C, Chronic
/
Angiogenesis Inhibitors
/
Antibodies, Monoclonal, Humanized
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Korean Journal of Ophthalmology
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS