A Comparison of the Effects of Different Doses of Butorphanol Administered in Conjunction with Ketorolac in Intravenous Patient Controlled Analgesia / 대한마취과학회지
Korean Journal of Anesthesiology
; : 12-17, 2003.
Article
in Ko
| WPRIM
| ID: wpr-40459
Responsible library:
WPRO
ABSTRACT
BACKGROUND: We designed a randomized study to assess the analgesic efficacy, side effects, and satisfaction score among different doses of butorphanol by using intravenous patient controlled analgesia (IVPCA) for pain relief following a cesarean section. METHODS: Sixty women who received a cesarean section were randomly divided into 3 groups. Each group received butorphanol 3 mg (Group 1), 5 mg (Group 2) or 7 mg (Group 3) with ketorolac 150 mg. Butorphanol and ketorolac were administerd by a two day infusor at the rate of 2 ml/hr. Assessments for pain with NRS, and side effects were evaluated in the recovery room, at 3 hr, 6 hr, 12 hr, 24 hr and 48 hr after the operation. A patient satisfaction score was evaluated at 24 hr and 48 hr after the operation. RESULTS: Pain score at 3 hr after the operation was significantly lower ine Group 2 than Group 1 (P<0.05), at 6 hr and 12 hr after the operation was significantly lower in Group 2 and Group 3 than Group 1 (P<0.05). However, there was no significant difference between Group 2 and Group 3. Patient satisfaction score at 24 hr and 48 hr after the operation did not show any significant difference among the three groups. One patient in Group 2 revealed sedation over 3 on a 4-point scale at 3 hr after the operation, but there was no significant difference among the three groups. CONCLUSIONS: The above results suggested that both butorphanol 5 mg and 7 mg with ketorolac 150 mg via IVPCA were an effective dosage for postoperative pain control during two days after a cesarean section without any significant side effects.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Pain, Postoperative
/
Recovery Room
/
Infusion Pumps
/
Butorphanol
/
Cesarean Section
/
Analgesia, Patient-Controlled
/
Patient Satisfaction
/
Ketorolac
Type of study:
Clinical_trials
Limits:
Female
/
Humans
/
Pregnancy
Language:
Ko
Journal:
Korean Journal of Anesthesiology
Year:
2003
Type:
Article