Marburg I polymorphism of Factor Ⅶ-activating protease and cerebral infarction / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 1171-1175, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-404797
ABSTRACT
Objective To determine the relation between Marburg I polymorphism of FactorⅦ-activating protease (FSAP) and cerebral infarction,and to analyze whether it is one of the risk factors of cerebral infarction.Methods Single strand conformation polymorphism-polymerase chain reaction (SSCP-PCR) was applied for the polymorphism analysis of FSAP in 159 patients with cerebral infarction and 179 non-cerebral infarction subjects.Results The phenotypes of FSAP in both the patients and the control subjects were wild type GG;no mutant of Marburg I was found. But a new gene mutation was tested, which had not been reported, requiring further investigation. Conclusion Marburg I polymorphism of FSAP may not be associated with cerebral infarction.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Risk factors
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2009
Type:
Article
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