Relationship between homocysteine level and peripheral artery disease in patients with newly-diagnosed type 2 diabetes / 中国糖尿病杂志
Chinese Journal of Diabetes
; (12): 913-914, 2009.
Article
in Zh
| WPRIM
| ID: wpr-405147
Responsible library:
WPRO
ABSTRACT
Objective To observe the association between homocysteine (Hcy)level and low limb vascular disease(LLVD) in newly-diagnosed type 2 diabetic patients. Methods The study subjects were divided into three groups : control group (NC), newly-diagnosed type 2 diabetes group without peripheral artery disease (T2DM) and peripheral artery disease with newly-diagnosed type 2 diabetes group (T2DM+LLVD).Both Hcy and the ankle-brachial index(ABI) were measured in three groups. Results Compared with NC group, clinical parameters of body mass index,waist-to-hip ratio,systolic blood pressure, total cholesterol(TC),triglycerides(TG),low density lipoprotein-cholesterol(LDL-C),and glycated hemoglobin A1C (HbA1c) increased markedly,and the content of high density lipoprotein-cholesterol (HDL-C) was markedly lower in both T2DM and T2DM+LLVD groups.In T2DM+LLVD group the contents of Hcy,LDL-C and HbA1c were markedly higher than in T2DM group,but the content of HDL-C decreased significantly.Hcy was independently associated with the development of peripheral artery disease in newly-diagnosed type 2 diabetic patients by logisitic regression analysis. Conclusions Increased Hcy is an independent risk factor for peripheral artery disease in newly-diagnosed type 2 diabetes.
Full text:
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Index:
WPRIM
Type of study:
Diagnostic_studies
/
Risk_factors_studies
Language:
Zh
Journal:
Chinese Journal of Diabetes
Year:
2009
Type:
Article