Effect of UVA irradiation on proliferation and NO/iNOS system of human skin fibroblast

Mingliang CHEN; Guiying ZHANG; Mei YI; Xiao CHEN; Ji LI; Hongfu XIE; Xiang CHEN

Effect of UVA irradiation on proliferation and NO/iNOS system of human skin fibroblast / 中南大学学报(医学版)

Mingliang CHEN; Guiying ZHANG; Mei YI; Xiao CHEN; Ji LI; Hongfu XIE; Xiang CHEN.

Journal of Central South University(Medical Sciences) ; (12): 705-711, 2009.

Article in Chinese | WPRIM | ID: wpr-405822

ABSTRACT

ABSTRACT

dosage ( P<0.01).Conclusion UVA can inhibit the proliferation activity of human skin fibroblasts. It might be related to the up-regulation of iNOS gene expression and the over-secretion of NO induced by UVA.

ultraviolet A (UVA); fibroblasts; survival rate; inducible nitric oxide synthase (iNOS); nitric oxide (NO)

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Central South University(Medical Sciences) Year: 2009 Type: Article