The therapeutic effect of Nitazoxanide on the dogs infected with Giardia canis / 中国兽医学报

ABSTRACT

To observe the therapeutic effect of Nitazoxanide(NTZ) on dogs infected with Giardia canis trophozoites.Eight dogs were infected with Giardia canis trophozoites and divided into four groups rondomly,G12 dogs treated with Nitazoxanide at a single dose of 1 mg/kg body weight;G22 dogs treated with NTZ at a single dose of 2 mg/kg;G32 dogs treated with NTZ at a single dose of 41 mg/kg;G42 dogs treated without drugs as control.All groups were examined for Giardia canis cysts by Zinc Sulfate Flotation.Each group was subjected to collect stool per day and counted cysts.The results of G2 and G3 were negative after 1th day.G1 were negative after 4th days.The results indicated that NTZ at a dose of 2 mg/kg and 4 mg/kg in dogs had a faourable effect on the dogs infected with Giardia canis.