Comparative analysis of immunological detection results in patients with POEMS syndrome / 国际检验医学杂志
International Journal of Laboratory Medicine
;
(12): 890-891, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-406860
ABSTRACT
Objective To investigate the immunological feature, and to provide evidence for di-agnosis and treatment of POEMS syndrome. Methods The results detected with serum protein elec-trophoresis (SPE), immunofixation (IFE) and immunoglobulin quantitative assay were retrospectively compared and analyzed in 27 patients with POEMS syndrome. Results For 27 cases of POEMS syn-drome, the detection rate of M protein was significantly higher detected with IFE than that with SPE. Among M protein, IgA was much more frequent than IgG (16 cases vs 5 cases), and all were typeλ. Besides, there was statistical difference in SPE results between 16 cases of POEMS syndrome with M protein positive (detected with SPE) and healthy controls. Conclusion Negative M protein result can't exclude the diagnosis of POEMS syndrome. Further evidence should be searched for, and the clinical data should be emphasized
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
International Journal of Laboratory Medicine
Year:
2008
Type:
Article
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