Clinical Analysis of Herpes Simplex Keratouveitis

ABSTRACT

A retrospective study was done to analyze the clinical characteristics about herpes simplex keratouveitis. We reviewed medical records of 28 patients who had been diagnosed as having herpes simplex keratouveitis at Hanyang University Hospital from May 1987 to January 1998. Mean follow-up period was 14 months. In 28 patients(male 19, female 9), first attack was in 5 patients, recurrent uveitis in 16 patients, and 7 patients were undetermined due to lack of detailed clinical history, Stromal keratitis(intersititial keratitis, kisciform keratitis, and necrotizing keratitis) was present in 23 eyes, superficial keratitis(dendritic keratitis, geographic eyes. Ten eyes had an increased intraocular pressure of 21mmHg or more, with 5 eyes having 31mmHg or more, which were all in cases of recurrence. Posterior synechiae were present in 9 eyes, iris atrophy in 4 eyes. Herpes simplex keratouveitis is prone to recur and frequently associated with herpes simplex keratitis, especially stromal keratitis. It may be associated with increased intraocular pressure, osterior synechiae, iris atrophy, or hypopyon, Therefore it is necessary to follow up persistently.