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A Case of Primary Extragastrointestinal Stromal Tumor Presenting as Peritoneal Dissemination / 대한소화기학회지
The Korean Journal of Gastroenterology ; : 319-323, 2010.
Article in Korean | WPRIM | ID: wpr-40784
ABSTRACT
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract, but also occurs at a lower frequency in extra-gastrointestinal regions such as omentum, mesentery, retroperitoneum and undefined abdominal sites. This tumor is called extragastrointestinal stromal tumor (EGIST). EGIST is mostly diagnosed as a cystic mass, but rarely occurs as a disseminated abdominal tumor. We experienced a 70-year-old man with primary EGIST presenting as peritoneal dissemination. Abdominal CT showed diffuse peritoneal thickening with a large amount of ascites, but no definite mass lesion. Laparoscopic biopsy was performed and histologic findings showed tumor composed of epithelioid cells. In the results of immunohistochemical stains, the tumor showed positive reactivity with CD117 (c-kit), CD34, vimentin and actin, but negative reactivity with desmin and S-100 protein. On account of unresectability and histologic parameters of malignant behavior, he was started on imatinib.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Peritoneal Neoplasms / Vimentin / Tomography, X-Ray Computed / Actins / Laparoscopy / Proto-Oncogene Proteins c-kit / Antigens, CD34 / Gastrointestinal Stromal Tumors / Positron-Emission Tomography Limits: Aged / Humans / Male Language: Korean Journal: The Korean Journal of Gastroenterology Year: 2010 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Peritoneal Neoplasms / Vimentin / Tomography, X-Ray Computed / Actins / Laparoscopy / Proto-Oncogene Proteins c-kit / Antigens, CD34 / Gastrointestinal Stromal Tumors / Positron-Emission Tomography Limits: Aged / Humans / Male Language: Korean Journal: The Korean Journal of Gastroenterology Year: 2010 Type: Article