Rheumatoid arthritis, traditional Chinese tongue demonstration and apoptosis / 中国组织工程研究

ABSTRACT

OBJECTIVE: To comprehend the development of research on rheumatoid arthritis (RA) and apoptosis so as to find the interrelationship and changing rules, probe into the apoptotic characteristics of RA.DATA SOURCES A computer-based search of Medline and foreign language books of National Science and Technology Library was performed for English literatures related to RA and apoptosis from January 1995 to December 2003 with the key words of "rheumatoid arthritis,apoptosis".Meanwhile, Chinese articles about RA, traditional Chinese tongue demonstration and apoptosis were searched in Chongqing Vip Database of Chinese Scientific and Technical Periodicals, Tsinghua Tongfang Database of Chinese Scientific and Technical Periodicals and Chinese CD Database of Literatures on Biomedicine with the key words of "rheumatoid arthritis,apoptosis, tongue demonstration".STUDY SELECTION Data were selected in the first searching, literatures on correlation between RA and apoptosis were searched in full-text.Accepting criteria ①Experimental researches about RA and apoptosis. ②Clinincal researchs about RA and apoptosis. ③Researches on traditional Chinese tongue demonstration and apoptosis. Excluded criteria Repetitive studies.DATA EXTRACTION A total of 82 researches about RA and apoptosis werecollected, 13 ones in which were in accordance with the accepting criteria. Of the 69 excluded articles, 58 ones were repetitive studies and 11 ones were reviews.DATA SYNTHESIS: Of 13 literatures, 11 ones were checked by experimental research and clinical research. It was found from the examinations of synovium of joint and peripheral blood (PB) that there were abnomal apoptoses in RA, which indicated that the invasion, nature of drug and physical therapy were in relation to the apoptosis of synovial cells. Rest 2articles were researches on apoptosis of tongue demonstration of other diseases, which indicated that the apoptosis of tongue demonstration related to the pathology of disease. By now, there were no reports about RA, tongue demonstration and apoptosis, which indicated that there were still some blank in research about the correlation between traditional Chinese tongue demonstration and apoptosis.CONCLUSION: There is superiority in the treatment of RA with combined treatment of traditional Chinese medicine and western medicine. It is demonstrated in the literatures that treatment against RA at present may be done by affecting the apoptosis of RA. Researches on type of syndromes of traditional Chinese medicine and apoptosis is limited to a minority of one or two diseases, and tongue demonstration are an important part in the diagnosis on symptoms, therefore, the interrelationship of RA (or tongue demonstration) apoptosis needs to be investigated, Therefore, the inner relationship between tongue demonstration of RA and apoptosis needs investigation so as to furtherly reveal the formation mechanism of tongue demonstration.