Experimental study on expression of TNF-α and ICAM-1 in cerebral ischemia-reperfusion injury / 中国组织工程研究
Chinese Journal of Tissue Engineering Research
;
(53): 2968-2969, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-410125
ABSTRACT
Objective To detect the expression of TNF α and ICAM 1 in cerebral ischemia reperfusion injury. To explore their probable modulation mechanism.Methods Immunohistochemistry was used to examine the expression of TNF α and ICAM 1.The MPO activity was determined by spectrophotometry.Result The expression of TNF α and ICAM 1 were obviously rised after cerebral ischemia reperfusion (P< 0.05).Conclusion The up regulation of TNF α and ICAM 1 after cerebral ischemia reperfusion induced the accumulation of leukocytes, which involved in ischemia reperfusion injury mechanism. TNF α play an important role in expression of ICAM 1.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Tissue Engineering Research
Year:
2002
Type:
Article
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