Effects of esculentoside A on production of IL-1 and TNF by rabbit synovial cells / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12): 425-426, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-410402
ABSTRACT
Objective:
To investigate the influence of esculentoside A(EsA) on production of IL-1 and TNF by rabbit synovial cells induced by LPS.Methods:
levels of IL-1 and TNF in the supernatant of rabbit synovial cell were determined by examining proliferation of thymic cells and by bioassay L929 cells as target cells, respectively.Results:
EsA in 5-40 μg/ml could significantly inhibit the production of IL-1 and TNF from rabbit synovial cells induced by LPS.Conclusion:
EsA can inhibit the production of IL-1 and TNF from synovial cells. It suggests that EsA may play a role in improving the rheumatoid arthritis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
2001
Type:
Article
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