Citicoline in treating neuroleptic-induced extrapyramidal side effect / 中国新药与临床杂志
Chinese Journal of New Drugs and Clinical Remedies
;
(12): 185-187, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-410974
ABSTRACT
AIM:To study the effects of citicoline in treating neuroleptic-induced extrapyramidal side effect (EPS). METHODS:Seventy-five patients were divided into two groups:citicoline group of 38 patients ( M25,F13;age 28 a±s 9 a) received citicoline injection 0.5 g.d-1,in 5 % glucose injection 500 mL,iv,drip,qd ,for 14 d and control group of 37 patients ( M23,F14;age 27 a±6 a) received 5 % glucose injection 500 mL,iv, drip, qd,for 14 d. RESULTS:
The total efficacy of citicoline or control group was 92 % and 11 % (P<0.05 ), respectively.The tremour, muscular rigidity, gait and muscle dystonia were better in citicoline group than in control group. No side effects were found.CONCLUSION:
Citicoline is effective for neuroleptic-induced EPS.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of New Drugs and Clinical Remedies
Year:
2001
Type:
Article
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