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Effect of TGF-β on collagen degradation of rabbit keratocytes / 吉林大学学报(医学版)
Journal of Jilin University(Medicine Edition) ; (6): 153-155, 2001.
Article in Chinese | WPRIM | ID: wpr-411027
ABSTRACT

Objective:

To observe the effect of TGF-β1 on collagen degradation of rabbit keratocytes.

Methods:

The activity of collagen degradation of keratocytes with three-dime nsional culture in collagen gel was determined with spectrophotometer.

Results:

TGF-β inhibited collagen degradation of keratocytes in dose-dependent manner.

Conclusion:

The present result suggests that TGF-β1 has the inhibitory effect on collagen degradation of keratocytes and may help in the treatment of corneal ulceration.
Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Jilin University(Medicine Edition) Year: 2001 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Jilin University(Medicine Edition) Year: 2001 Type: Article