Oxidative modification of rat β2-glycoprotein Ⅰ / 吉林大学学报(医学版)
Journal of Jilin University(Medicine Edition)
;
(6): 117-118, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-411031
ABSTRACT
Objective:
To investigate oxidative modification of β2-glycoprotein Ⅰ in vit ro.Methods:
Rat β2-glycoprotein Ⅰ was purified and characterized,then oxidize d by hypoxanthine plus xanthine oxidase as a supreroxide free radical generating system;carbonl groups of β2-glycoprotein Ⅰ were detected by the reaction w ith 2,4-dinitrophenylhudrazine.Results:
There was a significant increase of carbonyl groups formation in β2- glycoprotein Ⅰ oxidized in comparison with native β2-glycoprotein Ⅰ (P <0.05).Conclusion:
Carbonyl groups have been formed in vitro on rat β2-glycoprotein Ⅰ after oxidative modification using hypoxanthine plus xanthine oxidase system.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Jilin University(Medicine Edition)
Year:
2001
Type:
Article
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