Study on n-Hexane-induced Lipid Peroxidative Injuries in Rats / 环境与健康杂志
Journal of Environment and Health
;
(12): 86-88, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-411147
ABSTRACT
Objective To study the mechanism of toxicity of hexane. Methods SD rats inhaled 15 g/ma n-hexane statically for 8 hours. Results The levels of GSH in whole blood of rats declined significantly (t-test,P<0. 01). The levels of MDA in serum of rats revealed increasing trend but without statistical significance (t-test,P>0. 05). The activities of SOD and GSH-Px in liver of rats decreased significantly (t-test,P<0.01). Conclusion n-Hexane could induce or enhance the reaction of oxygen free radical in organism,and result in damages of lipid peroxidation,which might be one of the mechanisms of the toxicity of alkane.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Environment and Health
Year:
2001
Type:
Article
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