Quantitative thermal perception testing and quantitative vibratory sensation testing in Guillain-Barre syndrome and periphery polyneuropathy / 中国神经精神疾病杂志

ABSTRACT

Objective 　To evaluate the quantitative sensory testing in Guillain-Barre syndrome (GBS) and polyneuropathy (PNP). Methods　The quantitative sensory test (QST) was performed with Thermal Sensory Analyzer(TSA-2001) and Vibratory Sensory Analyzer(VSA-6003). Thermal and vibratory sensory tests were performed in the left patients with GBS or PNP and healthy subjects, on four sites of the left limbs by the method of Limits. Stimultaneously sensory conduction velocity (SCV) was measured. Results　There were increased TT and VT on distal limbs in the patients with GBS (with or without the symptoms or signs of disturbance of sensation) and PNP. QST in GBS and PNP was more sensitive than the clinical examination and SCV. There was significant association between VT and SCV in GBS, but not a significant association between TT\, VT and SCV in PNP. There was a paradoxical heat sensation in two patients with uremic PNP. Conclusions　QST is a sensitive and reliable test and can be a useful test in the diagnosis of PNP.