The Plasma Vitamin A and Subsets of T Lymphocyte in Lung Cancer Patients / 中国医科大学学报
Journal of China Medical University
;
(12): 133-134, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-411460
ABSTRACT
Objective:
Our aims were to evaluate the plasma vitamin A status and the function of T-cell dependent immunity in lung cancer patients, so as to explore the correlation between them. Methods:We measured the plasma vitamin A status with HPLC and checked the subsets of T lymphocyte with indirect immunofluorescence technique. Results: The levels of plasma vitamin A in lung cancer patients and in controls were(0.406±0.111)mg/L and(0.548±0.149)mg/L respectively . There was a significant difference between them(P<0.001) . The levels of CD3, CD4,and CD4/CD8 were lower in lung cancer patients than those in controls, while the level of CD8 was higher. The plasma vitamin A had positive correlation with CD3 , CD4,and negative with CD8. Conclusion: There is defect of the plasma vitamin A and low level of the function of T cell dependent immunity in lung cancer patients,which shows the obvious correlation between them. This research supplies the basis of clinical therapy to lung cancer with vitamin A.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of China Medical University
Year:
2001
Type:
Article
Similar
MEDLINE
...
LILACS
LIS