The Effects of Inhalation of Aerosolized Low Molecular Weight Heparin on the Clotting Time in Guinea Pigs and Bleeding Time in Mice / 中国药房
China Pharmacy
;
(12): 82-83, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-411531
ABSTRACT
AIM:
To study the effects of inhalation of aerosolized low molecular weight heparin(LMWH)and standard heparin(SH) on the clotting time and bleeding time in guinea pigs and mice.METHODS:
Guinea-pigs and mice inhaled aersolized LMWH and SH for 7 days,and the clotting time in guinea-pigs and tail bleeding time in mice were observed.RESULTS:
Compared with vehicle,LMWH 800IU/L,400IU/L and SH 800IU/L,400IU/L had no significant effects on the clotting time in guinea-pigs and tail bleeding time in mice(P>0.05);There were no significant differences between LMWH 800IU/L,400IU/L and SH 800IU/L,400IU/L(P>0.05).CONCLUSION:
Inhalation of aerosolized LMWH and SH had no significant effects on clotting time and bleeding time in animals.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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