Change of synaptophysin in rat model hippocampal formation after pentylenetetrazol kindling / 临床神经病学杂志
Journal of Clinical Neurology
; (6): 30-32, 2001.
Article
in Zh
| WPRIM
| ID: wpr-411697
Responsible library:
WPRO
ABSTRACT
Objective To study the plasticity of hippocampal formation in epilepsy.Methods The optical density (OD)of synaptophysin positive immunoreactive product was examined by image pattern analysis instrument in hippocampus of pentylenetetrazol induced kindling epileptic rats. The examined areas included CA1,CA3 and the dentate gyrus.Results The OD of synaptophysin positive immunoreactive product in hippocampal formation of kindling group was higher than the controls,especially in the mossy fiber layer of the area CA3 and the inner molecular layer in the dentate gyrus. Conclusion The change of synaptophysin resulted from kindling, it also could result in the molecular elements of kindling maintenance.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
Journal of Clinical Neurology
Year:
2001
Type:
Article