Mitochondrial Transmembrane Potential and Cell Apoptosis / 生物化学与生物物理进展
Progress in Biochemistry and Biophysics
;
(12): 3-6, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-411752
ABSTRACT
Apoptosis, an intrinsic cell death model which is regulated by organisms, is essential for the maintenance of tissue homeostasis in multicellular organisms. Recently, researchers on cell apoptosis have paid more attention on mitochondrion than on nucleus. Different death stimulus induces opening of PT pore, degradation of mitochondrial transmembrane potential, activation of caspase and inducing cell apoptosis. Bcl-2 and Bcl-XL inhibit cell apoptosis via mitochondrion while Bax, Bak and Bad induce apoptosis by means of regulation of mitochondrion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Progress in Biochemistry and Biophysics
Year:
2001
Type:
Article
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