Experimental pathology study on the effect of ACR on axon of both Ola mice and 6J mice / 吉林大学学报(医学版)
Journal of Jilin University(Medicine Edition)
;
(6): 573-576, 2000.
Article
in Chinese
| WPRIM
| ID: wpr-411800
ABSTRACT
Objective:
To observate the axon changes in pathology of Ola mice,compared with those of 6Jmice.Methods:
The peroneal nerve and sural nerve were studied by light-microscope and electronmi-croscope.Results:
In light-microscope,the total transverse fascicular area was significantly large ;density ofmyelinated fibers was significantly less;the maximal diameter of myelinated fibers was significantly less;minimal diameter of myelinated fibers had no changens in 6J mice. The Ola mice were nomal. In electronmi-croscope observation, the neurofilament was accumulated within axons.Conclusion:
In Ola mice treatedwith ACR,the like-Wallerian degeneration wes delayed. However,in 6J mice the neurofilament and mito-chondria accumulation was found within axons.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Jilin University(Medicine Edition)
Year:
2000
Type:
Article
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