ADVANCES IN TELOMERASE ACTIVITY OF GASTRIC CANCER / 中国普外基础与临床杂志
Chinese Journal of Bases and Clinics in General Surgery
;
(12): 56-58, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-412010
ABSTRACT
Objective To introduce telomeres, telomerase and their expression in gastric carcinoma. Methods The related literatures were collected and reviewed.Rsults In summary, telomerase activity could be detected in 85%-90% of gastric cancer. Moreover, the patient with telomerase-positive tumors showed poorer prognosis than those with telomerase-negative tumours, indicating that telomerase-positive gastric cancer might have more malignant potential. Conclusion Knowledge of telomerase activity in gastric cancer may be useful in cancer diagnosis, as well as a prognostic indicator of clinical outcome. Future development of drugs aimed at telomerase inhibition may potentially provide a therapy with relatively less side effects.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Bases and Clinics in General Surgery
Year:
2001
Type:
Article
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