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ADVANCES IN TELOMERASE ACTIVITY OF GASTRIC CANCER / 中国普外基础与临床杂志
Chinese Journal of Bases and Clinics in General Surgery ; (12): 56-58, 2001.
Article in Chinese | WPRIM | ID: wpr-412010
ABSTRACT
Objective To introduce telomeres, telomerase and their expression in gastric carcinoma. Methods The related literatures were collected and reviewed.Rsults In summary, telomerase activity could be detected in 85%-90% of gastric cancer. Moreover, the patient with telomerase-positive tumors showed poorer prognosis than those with telomerase-negative tumours, indicating that telomerase-positive gastric cancer might have more malignant potential. Conclusion Knowledge of telomerase activity in gastric cancer may be useful in cancer diagnosis, as well as a prognostic indicator of clinical outcome. Future development of drugs aimed at telomerase inhibition may potentially provide a therapy with relatively less side effects.
Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Bases and Clinics in General Surgery Year: 2001 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Bases and Clinics in General Surgery Year: 2001 Type: Article