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EGF、TNF、 SOD levels and hemorrheological changes in patients with diabetic retinopathy / 眼科新进展
Recent Advances in Ophthalmology ; (6): 350-352, 2000.
Article in Chinese | WPRIM | ID: wpr-412339
ABSTRACT
Objective To investigate the change of epithelium growth factor(EGF), tumor necrosis factor (TNF), superoxide dismutese(SOD) and hemorrheology (HL) in patients with diabetic retinopathy.Methods EGF、TNF、SOD levels and HL changes have been measured in 30 NIDDM patients with retinopathy (DR group), 29 NIDDM patients without retinopathy (NDR group), and 29 patients with senile cataract and without diabetes as control (C group). Results The mean levels of EGF、TNF and blood viscosity were significantly higher in both DR and NDR group than those in C group; the mean levels of SOD was significantly lower in both DR and NDR group than that in C group. The EGF、TNF and blood viscosity was significantly higher in proliferative type DR than in background DR; The SOD was significantly lower in proliferative type DR than in background DR.Conclusion The development of diabetic retinopathy is related to the increase of EGF、TNF、blood viscosity and decrease of serum SOD.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Recent Advances in Ophthalmology Year: 2000 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Recent Advances in Ophthalmology Year: 2000 Type: Article