γ-amino butyric acid transporter and epilepsy / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 261-263, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-412791
ABSTRACT
According to 5 different subtypes of γ-amino butyric acid transporter(GAT)in brain regions and subcellular distribution.GAT1 and GAT3 are closely related with occurrence and development of epilepsy.The abnormal expression of GAT or their function damaged contribute to hyperexcitable neurons In seizures.GABAergic inhibit circuit reduces and the down-regulation of GAT expression,primary up-regulation of GAT expression is a reactive changes or cause of epilepsy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2011
Type:
Article
Similar
MEDLINE
...
LILACS
LIS