Cox regression analysis on main influencing factors of recurrent stroke / 中国基层医药

ABSTRACT

Objective To explore the main influencing factors of recurrent stroke.Methods 2 065 new stroke patients were selected as study populations.The recurrent stroke status and kinds of influencing factors were followed up.The follow-up study time was 3 years.Single factor and multi-factor analysis methods were carried out for influencing factom of recurrent stroke by Cox proportional hazaIds regression models.Results By the end.1 881 pa%);45 patients were recurrent in 6accepted visit,184 were lost follow-up.327 patients were recurrent(17.38tients months(13.76%);68 patients were recurrent during 6 months to 1 year(20.80%);97 patients were recurrent during 1 year to 2 years(29.66%);117 patients were recurrent after 3 years(35.78%).Single factor Cox regression analysis:The risk factors of recurrent stroke were advanced age(RR=1.48),smoking(RR=1.35),fat intake(RR=1.83),hypertension history(RR=2.54),diabetes history(RR=1.72),high lipemia(RR=1.83),stroke family history(RR=2.62),depression(RR=1.84),life events(RR=2.53),fibrinogen(RR=1.75),carotid plaques(RR=2.68);The protecting favors of recurrent stroke were female(RR=0.64),sports(RR=0.33),social support(RR=0.36).Multi-factor Cox regression analysis:the risk factors of recurrent stroke were hypertension history(RR=1.86),high lipemia(RR=1.95),stroke family history(RR=2.62),life events(RR=2.38),carotid plaques(RR=2.77);The protecting factors of recurrent stroke were sports(RR0.35),social support(RR=0.32).Conclusion The prevention of hypertension history,high lipemia,the family history of stroke,more supports and the high ability of answering life events could help to prevent the recurrent stroke.