Effect of p38MAPK in icariin induced osteoblast differentiation / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 122-124, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-413808
ABSTRACT
This paper was aimed to investigate the effects of icariin on the expression of p38 mitogen activated protein kinase(MAPK)protein in rat osteoblasts cultured in vitro, to elucidate the signal transduction of icariin in preventing and treating osteoporosis. The results showed that p38MAPK could be activated by icariin within 5min, and Cbfal could also be upregulated, and SB203580, an inhibitor of p38MAPK pathway, could partly inhibit Cbfal upregulation by icariin.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Endocrinology and Metabolism
Year:
2011
Type:
Article
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