Expression of CD40 in spleen in cirrhotic portal hypertension and its clinical significance / 中华肝胆外科杂志
Chinese Journal of Hepatobiliary Surgery
;
(12): 302-304, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-413934
ABSTRACT
ObjectiveTo investigate the expression and clinical significance of CD40 in the spleen of cirrhotic portal hypertension. MethodsExpression of CD40 was determined with S-P immunohistochemistry in spleen specimens from 50 cases of cirrhotic portal hypertension and 15 healthy individuals. ResultsThe CD40 positive rates in normal spleen and cirrhotic spleen were 86.7% and 36.0%, respectively. There was a significant difference between the 2 groups (P<0.05). There was a negative correlation between the expression of CD40 and Child grades of liver function and cirrhotic splenic types(P<0. 05). Conclusion CD40 might reflect the changes of splenic immune function,which might be one of more exact clinical examination indexes of splenic immune function.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Hepatobiliary Surgery
Year:
2011
Type:
Article
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