Mechanisms of ginsenoside and oridonin inducing cancer cell apoptosis / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 263-266, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-414598
ABSTRACT
Apoptosis plays a critical role in tumor genesis and progression. Induction of cancer cell apoptosis with traditional Chinese medicines is at present a hot topic in the research of cancer therapy. It has been found that many active components of traditional Chinese medicines can induce cancer cell apoptosis; ginsenoside and oridonin are two of them that have been studied relatively thoroughly. The mechanisms that ginsenoside and oridonin induce cancer cell apoptosis include arresting cell cycle progression, up-regulating expression of apoptotic promoting proteins, down-regulating expression of apoptotic inhibiting proteins, and activating caspase cascade.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2011
Type:
Article
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