Progress in the BRAFV600E mutation and papillary thyroid carcinoma / 国际外科学杂志
International Journal of Surgery
;
(12): 104-109, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-414710
ABSTRACT
BRAFV600E mutation is the most common genetic alteration in the papillary thyroid carcinoma.It plays an important role in the tumorigenesis,invasiveness and metastasis of the papillary thyroid carcinoma.Testing of BRAFV600E mutation is of great value in diagnosis,which also can be used as a prognostic maker of papillary thyroid cancer.Inhibitors treatment targeted to BRAF kinase and its downstream effectors is a new area in the treatment of BRAFV600E mutated thyroid cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Surgery
Year:
2011
Type:
Article
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