Role of CXCR4 expression in progress and prognosis of breast cancer / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 36-38, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-414737
ABSTRACT
CXCR4, a receptor for stromal cell-derived factor-1 (SDF-1, also know as CXCL12) and a member of the chemokine receptor family, has been shown to play an important role in the proliferation, migration, invasion and metastasis of breast cancer cells. CXCR4 expression is an early event in breast cancer development and may serve as a biomarker for early detection and diagnosis of breast cancer. Expression of CXCR4 has been demonstrated to correlate with metastasis and poor prognosis in breast cancer. Inhibition of CXCR4 expression may be a potential target of breast cancer treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
/
Screening study
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2011
Type:
Article
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