Research development of APC gene promoter methylation in gynecological cancer / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 428-430, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-415164
ABSTRACT
Adenomatous polyposis coli gene is an important anti-oncogene of the Wnt signaling pathway. The promoter hypermethylation of APC gene can effect the expression of APC mRNA and APC proteinum, which can make Wnt signaling pathway anomalous. Recently. the promoter hypermethylation of APC Gene in gynecological tumors is found in many studies, and it is related to the aggravation level of tumor.This paper reviews the influencing factors and progress of promoter methylation of APC gene in Gynecological cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2011
Type:
Article
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