Effects of p90 ribosomal S6 kinase pathway in breast cancer and its mechanism / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 441-444, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-415185
ABSTRACT
p9O ribosomal S6 kinases(BSKs)are overexpressed in 50% human breast cancer. RSKs enhance the proliferation of breast cancer cells by regulating several key breast cancer-related proteins. They also improve survival of the breast cancer cells through regulating translocation and translation of mRNA. In addition. RSK promotes tumor angiogenesis by interaction with estrogen receptor. However, RSK4 may play an inhibitory role in breast cancer. In general, except RSK4,RSKs may become promising targets of breast cancer therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2011
Type:
Article
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