Association of cytokine IL-10 levels with cachexia from patients with low-third gastric cancer / 肠外与肠内营养
Parenteral & Enteral Nutrition
; (6): 69-71, 2010.
Article
in Zh
| WPRIM
| ID: wpr-415298
Responsible library:
WPRO
ABSTRACT
Objective: To explore the association of the serum levels of cytokine IL-10 with the occurrence of cachexia from patients with low-third gastric cancer. Methods: Radioimmunoassay was used to examine the serum levels of IL-10 in 150 patients with low-third gastric cancer and 135 healthy controls. Results: The serum levels of IL-10 were significantly higher in patients with low-third gastric cancer than controls(Z=-11.862, P<0.01). The serum levels of IL-10 were significantly higher in patients with low-third gastric cancer of clinical stageⅢ/Ⅳ than those with clinical stageⅠ/Ⅱ(Z=-10.028, P<0.01). The serum levels of IL-10 were significantly higher in patients with cachexia than those without(Z=-10.369, P<0.01). Logistic regression analysis showed that IL-10 was associated with odds ratios of 1.599 (95%CI:1.299-1.870, P<0.01) for cachexia. Conclusion: The serum levels of IL-10 are possibly associated with the occurrence of cachexia from patients with low-third gastric cancer.
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Index:
WPRIM
Language:
Zh
Journal:
Parenteral & Enteral Nutrition
Year:
2010
Type:
Article