Hypoxia inducible factor-la and colorectal cancer / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 547-550, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-415891
ABSTRACT
HIF-1α, a transcriptional activator regulating cells and tissues' response to hypoxia, can induce expression of a variety of factors and facilitate adaptation to hypoxia. Tumor hypoxic microenvironment and expression of HIF-1α is closely related to the occurrence of colorectal cancer, development, invasion, metastasis and prognosis, which becomes a hot spot in colorectal cancer research. To further clarify the process of colorectal cancer and to explore new treatment methods in colorectal cancer, HIF-1α in colorectal cancer studies was briefly reviewed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2011
Type:
Article
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