Maternal and Perinatal Outcomes of Early- and Late-onset Preeclampsia / 대한주산의학회잡지
Korean Journal of Perinatology
; : 370-380, 2009.
Article
in Ko
| WPRIM
| ID: wpr-41819
Responsible library:
WPRO
ABSTRACT
PURPOSE: Early-onset preeclampsia is thought to be associated with fetal mortality and maternal complications. We compared maternal clinical characteristics, complications, and perinatal outcome between early- and late-onset preeclampsia. METHODS: We analysed retrospectively 212 pregnant women with preeclampsia between 2004 and 2008 at a tertiary university hospital. We divided preeclamptic women as early-onset (n=58), with an onset before 32 weeks gestation, and late-onset (n=154), with an onset after 32 weeks gestation. We compared maternal characteristics, maternal complications, and neonatal outcomes between the two groups. RESULTS: There were no significant differences in maternal age, parity, BMI, previous history of preeclampsia, hypertension, and DM between early- and late-onset preeclampsia. Among the maternal complications, maternal blood pressure was higher in early-onset preeclampsia without any statistical significance, but the amount of 24 hours urine protein was significantly higher in early-onset preeclampsia than late-onset (P=0.003). There were significantly higher rate of visual disturbance, elevated liver enzyme, pulmonary edema and severe disease in early-onset preeclampsia (all P<0.05). Comparing neonatal outcome, there were higher rate of fetal death in uterus (FDIU) (P=0.0001), low Apgar score (P<0.0001), and perinatal death (P<0.0001) in early-onset preeclampsia. Fetal birth weight and onset of preeclampsia were significant covariate factors for perinatal mortality. CONCLUSION: Early-onset preeclampsia was related to poor perinatal and materanl outcomes, but there was no difference in maternal characteristics. Further studies are necessary for prediction, pathogenesis, and therapy of early-onset preeclampsia.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Apgar Score
/
Parity
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Pre-Eclampsia
/
Pulmonary Edema
/
Uterus
/
Birth Weight
/
Blood Pressure
/
Retrospective Studies
/
Maternal Age
/
Pregnant Women
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Female
/
Humans
/
Pregnancy
Language:
Ko
Journal:
Korean Journal of Perinatology
Year:
2009
Type:
Article