Effects of brain-derived neurotrophic factor and tvrosinekinase B in the disease of behavioral development in children / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 158-161, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-418365
ABSTRACT
Brain-derived neurotrophic factor(BDNF) is a key signaling molecule during the development of nervous system.When BDNF is binded tyrosine kinase receptor B ( Trk B ),it can lead to a variety of physiological effects.Although the mechanisms of their action remain unclear,studies have proved that they may be related to effects of nerve cell survival,growth,differentiation,repair after injury and apoptosis,etc.This review describes the affecting factors in the expression of BDNF and TrkB,the effects of BDNF and TrkB in the development of behavioral disorders and the relationship with early environment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2012
Type:
Article
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