Study on isolation of two components with biological activities from the Species of sponge Dysidea cinerea collected from Ha Long maritime area

ABSTRACT

Dys-1 and Dys-2 compounds were isolated and determined structure from extracts of n-hexane and dichloromethane of sponge Dysidea cinerea by normal and reverse phases of silica gel column chromatography. Dys-1 is a white crystallized agent. Through data and reference materials, the agent is determined as Isofucosterol (24-Stigmasta-5, 24(24')-dien-3β-ol). Dys-2 compound is a crystallized agent with crystal of white needle form. The compound is determined as 5, 8- epidioxycholest-6--en-3-ol. It is cyto-toxic against three tumor cell lines in human such as epithelium cancer, liver cancer, and uterus membrane cancer