Follow-up of the artificial heart valve replacement and analyze the long-term curative effect / 中国综合临床

ABSTRACT

Objective To review the clinical features and the follow-up results of 317 cases of patients treated with artificial heart valve replacement and evaluate the curative effect.Methods Data of 317 patients underwent artificial heart valve replacement from July 2005 to June 2010 was analyzed,among them,284 patients replaced with mechanical valve and 33 patients with biological valve.Clinical features including age,etiology,surgical approach,valve type,etc,were summarized and the recovery of cardiac function,the incidence of complication and mortality were observed through postoperative follow-up.Results There were 6 patients died in the perioperative period and 311 survived.Two hundred and ninety-one cases were followed up and the follow-up rate was 93.57％.The time of follow-up is 1.00 to 4.75 years( with average2.23 ±1.37 years).The cardiac function(NYHA) was significantly improved after operation ( grade2.05 ± 0.29 vs 3.17 ± 0.62 ) ( t =2.366,P ＜ 0.05 ).It was related to age,cardiac function before operation ( P ＜ 0.05 ).One patient died during the follow-up period.The statistics analysis showed that the long-term incidence of complication was related to the type of heart valve prosthesis ( P ＜ 0.05 ).Conclusion The therapeutic effect of artificial heart valve replacement surgery appears satisfactory.Heart function is improved significantly and the survival rate is high.Reasonable timing of surgery,appropriate type of prosthetic valve and intensified clinical follow-up can help to reduce the occurrence of postoperative complication.