Glycolysis abnormality in neoplasm cells and the targeted therapy / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 726-728, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-419364
ABSTRACT
Cancer cells display a decreased mitochondrial respiration along with an abnormal activation of glycolysis to satisfy the demand of the malignant growth even in the presence of oxygen.This phenomenon may be caused by mitochondrial dysfunction,hypoxia of microenvironment and the abnormal activation of upstream regulators of glycolysis pathway.Treatment targeted at the glycolysis pathway and its upstream regulators may provide a new therapeutic strategy of cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2012
Type:
Article
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